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KMID : 0605619990060010135
Journal of Korean Society of Biological Psychiatry
1999 Volume.6 No. 1 p.135 ~ p.141
A Case of Convulsive Seizure Development Induced by Clozapine
¼­¸¸±æ/Man Kil Seo
±èµµ°ü/±èÀÌ¿µ/Doh Kwan Kim/E Yong Kim
Abstract
The authors described a case of male schizophrenia who developed myoclonic jerk
repeatedly and one episode of convulsive seizure during the treatment of clozapine.
According to literatures and reported cases, myoclonic jerks induced in a small amount
of clozapine may precede and predict the development of a convulsive seizure. Therefore
clinicians have to pay attention to the development of a myoclonic jerk during the
administration of clozapine. They may decrease the dosage of clozapine step by step at
first in the convulsive state, and observe EEG changes of patients frequently.
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